here at laser crystal, we offer 3 types of branding methods for our crystal awards, trophies and paperweights. discover more at laser crystal.
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the results of the seventh blind test of crystal structure prediction are presented, focusing on structure generation methods.
this covers crystal family,what is crystal with its process flow,advantages & disadvantages of crystal method & how it is different from scrum
the results of the seventh blind test of crystal structure prediction are presented, focusing on structure generation methods.
crystal methodology is a flexible and collaborative approach to project management within the agile framework. developed by alistair cockburn, it offers a set of practices tailored to fit the unique needs of each project.
a guide to crystal method: biography, discography, reviews, best albums, ratings
crystal polymorphism is an important and fascinating aspect of solid state chemistry with far reaching implications in the pharmaceuticals, agrisciences, nutraceuticals, battery and aviation industries. late appearing more stable polymorphs have caused numerous issues in the pharmaceutical industry. experimental polymorph screening can be very expensive and time consuming, and sometimes may miss important low energy polymorphs due to its inability to exhaust all crystallization conditions. in this paper, we report a crystal structure prediction (csp) method with unprecedented accuracy and efficiency, validated on a large and diverse dataset including 65 molecules with 135 experimentally found polymorphic forms. the method combines a novel systematic crystal packing search algorithm and the first use of machine learning force fields in a hierarchical crystal energy ranking. our method not only reproduces all the experimentally known polymorphs, but also suggests new low energy polymorphs yet to be discovered by experiment that might pose potential risks to development of the currently known forms of these compounds. in addition, we also demonstrate, in two prospective drug development projects, how the method was used to accelerate clinical formulation design and derisk downstream processing. the high accuracy, reliability, and efficiency of our method with large scale validations and prospective studies position it for routine molecular crystal structure prediction in drug development.
a fabricated transparent ribcage facilitates real-time analysis of whole-lung function down to cellular resolution.
this book contains the proceedings of a nato advanced study institute entitled "characterization of crystal growth defects by x-ray methods' held in the university of durham, england from 29th august to 10th september 1979. the current interest in electronic materials, in particular silicon, gallium aluminium arsenide, and quartz, and the recent availability of synchrotron radiation for x-ray diffraction studies made this advanced study institute particularly timely. two main themes ran through the course: 1. a survey of the various types of defect occurring in crystal growth, the mechanism of their different methods of generation and their influence on the properties of relatively perfect crystals. 2. a detailed and advanced course on the observation and characterization of such defects by x-ray methods. the main emphasis was on x-ray topographic techniques but a substantial amount of time was spent on goniometric techniques such as double crystal diffractometry and gamma ray diffraction. the presentation of material in this book reflects these twin themes. section a is concerned with defects, section c with techniques and in linking them. section b provides a concise account of the basic theory necessary for the interpretation of x-ray topographs and diffractometric data. although the sequence follows roughly the order of presentation at the advanced study institute certain major changes have been made in order to improve the pedagogy. in particular, the first two chapters provide a vital, and seldom articulated, case for the need for characterization for crystals used in device technologies.
collaborative, feedback-driven, and iterative when several people representing various software development methods convened at the lodge at snowbird ski resort, they all agreed to deliver excellent products (check our article about agile management to learn more). this would be done by operating in an environment which places people as the most important aspect of the...
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crystal polymorphism plays an important role in pharmaceuticals, agrisciences and other industries. here the authors present an efficient and accurate crystal structure prediction method with large scale validation and blind test.
practice scaling questions. scaling is the ability of the crystal methods to adapt to projects of varying sizes, complexities, and team compositions. different project situat…
posts about crystal methods (crystal clear) written by espirl
crystal is an agile methodology for software development. it focuses on people and communications over processes and tools and is uniquely flexible around team types, criticality and project priority.
scrum, crystal, extreme programming: which is the most popular framework? how can you choose the agile method that’s right for your company?
do you know the frameworks you might see when using agile? this is a video and article explaining crystal, one of the first agile frameworks. check it out!
the xchem facility at diamond light source offers fragment screening by x-ray crystallography as a general access user program. the main advantage of x-ray crystallography as a primary fragment screen is that it yields directly the location and pose of the fragment hits, whether within pockets of in …
listen to music from the crystal method like born too slow, name of the game & more. find the latest tracks, albums, and images from the crystal method.
crystal method is an agile software development approach that focuses primarily on people and their interactions when working on a project.
the crystal method · album · 2014 · 11 songs
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find out all you need to know about the crystal method in agile. also learn about the origin, functioning and principles of the crystal agile methodology.
crystal methodology emphasizes individuals and interactions over processes and tools. here’s what you need to know about this framework.
roger hiorns
the crystal agile framework emphasizes people rather than procedures, empowering teams to develop their solutions for each project. discover more with craft!
we prepare high quality bulk single crystals for physics research using a variety of melt and solution growth techniques; we have excellent facilities for sample preparation and characterisation.
an overview of the crystal family of methodologies
what is crystal agile framework? what are the pros & cons of the crystal agile framework, & when should you use it? we've explained everything here.
methods of agile software development have grown in number over the years. learn more about the xp, fdd, dsdm, and crystal methods here.
viscoelastic materials are often encountered in nature from biological matter, such as microbes and mammalian cells to non-biological matter such as polymers and even metals. studying these materials is often challenging due to their complex physical properties and many widely used methods are limited in their portability, simplicity, and the possibility for system integration. quartz crystal microbalance (qcm) is a tool which overcomes these limitations and can be used to gain insights into complex physical phenomena. using piezoelectricity, qcm gives us information about the environment it has been submerged in through parameters such as resonance frequency and dissipation. this immensely versatile tool has been chosen to tackle the problems explored in this project. two unsolved problems in the area of viscoelastic materials were chosen as subjects of this investigation.the first explored subject is bacterial detection, which is challenging at point-of-care (poc) with traditional methods due to the requirement of, slow detection times, high cost, and a need for laboratory infrustructure. qcm gives the potential to overcome these issues and in addition allow for portable online integration. poc bacterial diagnostics is necessary due to the increasing of antimicrobial resistance (amr) with non-specific use of antibiotics. qcm has shown potential for clinical bacterial detection in recent studies. recently, the anharmonic detection technique (adt) was presented as promoising but is yet to be validated for diagnosis of infections in complex biological samples and antibiotic susceptibility testing (ast). in this study the adt methodology was investigated and refined, leading to improved bacterial binding to qcm surface and enhanced transduction. for the first time adt was used in a bacterial infection setting, by detecting the infectious e. coli o111 strain in biological urine, mimicking a urinary tract infection. detection was achieved at a sensitivity of 106 cells/ml within a 50-minute test time. additionally, initial ast measurements were demonstrated with penicillin antibiotic. the second problem is from the area of charge storage which key for renewable energy. qcm was used to study novel amine based electrolytes for aluminium batteries. aluminium as a battery material overcomes several issues faced with lithium, most importantly availability and recyclability. the development of suitable electrolytes is a key hindrance for aluminium ion-batteries. the electrolytes studied in this project, although exhibiting promising electrochemical properties, are experimentally challenging due to their viscoelastic properties and complex viscosity behaviour during redox cycles. it was shown, how through qcm study, it was possible to extract crucial insight about the nature of these electrolytes and assess their potential for battery application. while electrochemical qcm (eqcm) is an established method for electrolyte studies, the unsolved problem exists of in-situ mass transport measurement for electrolytes exhibiting significant viscosity changes throughout the redox cycle, such as the electrolytes encountered in this research. in this work a new methodology is presented to overcome this issue, by using a model combining resonance frequency and dissipation data. it was shown that it can be used for in-situ measurements and has the potential to be applied for different electrolytes and electroplating applications.
what is the crystal framework for agile product development? here is a broad overview of this agile framework and its strengths and weaknesses.
understand what is crystal framework for product development. what are the variants within the crystal framework and which one to apply in your context
the crystal method is one of the most lightweight and flexible software development methods. it consists of crystal clear, crystal yellow, crystal red, and other agile methods with unique characteristics.
building a ligand into a weak region of an electron density map of a protein is a subjective process. here, the authors present a new method to obtain a clear electron density for a bound ligand based on multi-crystal experiments and 3d background correction.
alistair cockburn developed the crystal methods approach. his focus is on the people, interaction, community, skills, talents, and communications with the
crystal method is one of the most exciting new developments in card magic for a long time. complete with the crystal method gimmicks and full instructional dvd crystal method will allow you to... transfer signatures from card
agile — it’s a common term in the business world, and it involves many different methodologies that can cater to any kind of team.
university publications
i’m sure you know how the agile manifesto came into existence. 17 men met in a ski resort in 2001 and, although they had different approaches to software
listen to music by the crystal method on apple music.
explore agile crystal methods and learn about its principles, benefits, and how it compares to scrum and kanban, to determine if it's the right fit for your team.
crystal - crystal methodology is a series of agile methods established by alistair cockburn and jim highsmith. alistair cockburn refines the crystal methodology into crystal clear, crystal yellow, crystal orange, and crystal red. these crystal methodologies are divided according to the importance of the project and the size of the participants.
researchers can use crystallisation to uncover multiple aspects of reality and experience.
in this primer, we explore crystal agile methodology, its key development roles, and how to apply it within your own organization.
ucsb researchers unlock another piece of the puzzle that is crystal growth
the agile crystal methodology provides a unique flavor to the general agile approach to managing projects. this post defines what the agile crystal method is, key aspects of the mindset behind the crystal approach, strategic consideration, and impacts for project managers. what is the agile crystal method? crystal was introduced by alistair cockburn at ibm
in macromolecular crystallography, the rigorous detection of changed states (for example, ligand binding) is difficult unless signal is strong. ambiguous ('weak' or 'noisy') density is experimentally common, since molecular states are generally only fractionally present in the crystal. existing meth …
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agile crystal method is a family of agile software development methodologies that prioritize people / interactions over processes and tools.
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learn about the crystal agile methodology with our comprehensive guide. we will explore its core principles, benefits, and implementation steps.
find out what the crystal agile methodology is, who created it, when it's appropriate to use, and how the monday.com os work platform can help your team stay organized.
practice osmotic communication questions. osmotic communication is a concept in crystal methods that describes the free flow of information within a project team. it emphasiz…